RECENT PUBLICATIONS
2020

Musci, P.; Colella, M.; Sivo, A.; Romanazzi, G.; Degennaro, L.; Luisi, R.
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Flow Microreactor Technology for Taming Highly Reactive Chloroiodomethyllithium Carbenoid: Direct and Chemoselective Synthesis of α‑Chloroaldehydes
Organic Letters 2020, asap, doi:10.1021/acs.orglett.0c01085

Colella, M.; Tota, A.; Takahashi, Y.; Higuma, R.; Degennaro, L.; Nagaki, A.; Luisi, R
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Fluoro-substituted Methyllithium Chemistry Based on A Novel External Quenching Method Using Flow Microreactors
Angew. Chem. Int. Ed. 2020, asap, doi:10.1002/anie.202003831

Colella, M.; Nagaki, A.; Luisi, R.
Flow Technology for the Genesis and Use of (Highly) Reactive Organometallic Reagents.
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Open Access Review
Chemistry - A European Journal 2020, 26 (1), 19-32

Musio, B.;.et al.... Luisi, R.; Gallo, V.
A community-built calibration system: The case study of quantification of metabolites in grape juice by qNMR spectroscopy.
Talanta, 214. doi:10.1016/j.talanta.2020.120855

Takahashi, Y.; Ashikari, Y.; Takumi, M.; Shimizu, Y.; Jiang, Y.; Higuma, R.; Ishikawa, S.; Sakaue, H.; Shite, I.; Maekawa, K.; Aizawa, Y.; Yamashita, H.; Yonekura, Y.; Colella, M.; Luisi, R.; Takegawa, T.; Fujita, C.; Nagaki, A.,
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Synthesis of Biaryls Having a Piperidylmethyl Group Based on Space Integration of Lithiation, Borylation, and Suzuki–Miyaura Coupling.
European Journal of Organic Chemistry 2020, 2020 (5), 618-622.
2019

Briggs, E. L.; Tota, A.; Colella, M.; Degennaro, L.; Luisi, R.; Bull, J. A.
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Synthesis of Sulfonimidamides from Sulfenamides via an Alkoxy-Amino-λ6 -Sulfanenitrile Intermediate.
Angewandte Chemie International Edition 2019, 58, 14303-14310

Colella, M.; Tota, A.; Großjohann, A.; Carlucci, C.; Aramini, A.; Sheikh, N. S.; Degennaro, L.; Luisi, R.
Straightforward Chemo- and Stereoselective Fluorocyclopropanation of Allylic Alcohols: Exploiting the Electrophilic Nature of the Not so Elusive Fluoroiodomethyllithium.
Chemical Communications 2019, 55, 8430

Monticelli,S.; Colella, C.; Tota, A.; Pillari, V.; Langer, T.; Holzer, W.; Degennaro, L.; Pace, V.; Luisi, R.
Modular and Chemoselective Strategy for the Direct Access to α-Fluoroepoxides and aziridines via the Addition of Fluoroiodomethyl-lithium to Carbonyl-like Compounds
Organic Letters 2018, 22, 584

Musci, P.; Colella, M.; Fanelli, F.; Altomare, A.; Pisano, L.; Carlucci, C.; Luisi, R.; Degennaro, L.
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Stereo- and Enantioselective Addition of Organolithiums to 2-Oxazolinylazetidines as a Synthetic Route to 2-Acylazetidines.
Frontiers in Chemistry 2019, 7.

De Angelis, S.; Celestini, P.; Purgatorio, R.; Degennaro, L.; Rebuzzini, G.; Luisi, R.; Carlucci, C.
Development of a continuous flow synthesis of propranolol: tackling a competitive side reaction
Journal of Flow Chemistry 2019, 9, 231-236.

De Angelis, S.; Triminì, A.; Franco, M.; Degennaro, L.; Romanazzi, G.; Carlucci, C.; González, A.; Sainz, R.; Goñi, A.; Ferritto, R.; Aceña, J. L.; Luisi, R. Belén Cid, M.
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A Study of Graphene-Based Copper Catalysts: Copper(I) Nanoplatelets for Batch and Continuous-Flow Applications
Chemistry - An Asian Journal 2019, 14, 3011-3018.

Lauder, K.; Masci, D.; Toscani, A.; Al Mekdad, A.; Black, G. W.; Brown, N. L.; Turner, N. J.; Luisi, R.; Castagnolo, D.
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A facile and regioselective multicomponent synthesis of chiral aryl-1,2-mercaptoamines in water followed by monoamine oxidase (MAO-N) enzymatic resolution
Organic and Biomolecular Chemistry 2019, 17, 8982-8986.

Colella, M.; Musci, P.; Luisi, R.; Degennaro, L.
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Synthesis and use of halodifluoromethyl heterocycles
Targets in Heterocyclic Systems, 2019; Vol. 23; pp 384-398.

Carlucci, C.; Andresini, M.; Degennaro, L.; Luisi, R.
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Benchmarking acidic and basic catalysis for a robust production of biofuel from waste cooking oil.
Catalysts 2019, 9, 1050.

Carlucci, C.; Degennaro, L.; Luisi, R.
Titanium Dioxide as a Catalyst in Biodiesel Production.
Catalysts 2019, 9 (1), 75
2018


Colella, M.; Carlucci, C.; Luisi, R.
Supported Catalysts for Continuous Flow Synthesis
Topics in Current Chemistry 2018, 376, 46

Tota, A.; St John-Campbell, S.; Briggs, E. L.; Estévez, G. O.; Afonso, M.; Degennaro, L.; Luisi, R.; Bull, J. A.
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Highly Chemoselective NH- and O-Transfer to Thiols Using Hypervalent Iodine Reagents: Synthesis of Sulfonimidates and Sulfonamides.
Org. Lett. 2018, 20, 2599-2602

De Angelis, Hone, C.; Degennaro, L.; Celestini, P.; Luisi, R.; Kappe, O.
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Sequential α-Lithiation and Aerobic Oxidation of an Arylacetic Acid - Continuous-Flow Synthesis of Cyclopentyl Mandelic Acid
J. Flow. Chem. 2018, 8, 109–116

De Angelis, S.; Carlucci, C.; de Candia, M.; Rebuzzini, G.; Celestini, P.; Riscazzi, M.; Luisi, R.; Degennaro, L.,
Targeting a Mirabegron precursor by BH3-mediated continuous flow reduction process.
Catalysis Today 2018, 308, 81-85

Andresini, M.; De Angelis, S.; Uricchio, A.; Visaggio, A.; Romanazzi, G.; Ciriaco, F.; Corriero, N.; Degennaro, L.; Luisi, R.
Azetidine-Borane Complexes: Synthesis, Reactivity, and Stereoselective Functionalization.
J. Org. Chem. 2018, 83 (17), 10221-10230

Luisi, R.; Degennaro, L.,
Use of azetidine scaffolds in stereoselective transformations (microreview).
Chem. Heter. Comp. 2018, 54, 400-402

Carlucci, C.; Tota, A.; Colella, M.; Ronamazzi, G.; Clarkson, G. J.; Luisi, R.; Degennaro, L.
Use of Hypervalent Iodine in the Synthesis of Isomeric Dihydrooxazoles.
Chem. Heter. Comp. 2018, 54, 428-436

Colella, M.; Musci, P.; Carlucci, C.; Lillini, S.; Tomassetti, M.; Aramini, A.; Degennaro, L.; Luisi, R.
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1,3-Dibromo-1,1-difluoro-2-propanone as Useful Synthon for a Chemoselective Preparation of 4-Bromodifluoromethyl Thiazoles
ACS Omega, 2018, 3, 14841–14848
2017

Parisi, G.; Colella, M.; Monticelli, S.; Romanazzi, G.; Holzer, W.; Langer, T.; Degennaro, L.; Pace, V.; Luisi, R.
Exploiting a "beast" in carbenoid chemistry: Development of a straightforward direct nucleophilic fluoromethylation strategy.
J. Am. Chem. Soc. 2017, 139, 13648-13651
Denora, N.; Lopedota, A.; de Candia, M.; Cellamare, S.; Degennaro, L.; Mele, A.; Tricarico, D.; Cutrignelli, A.; Laquintana, V.; Altomare, C. D.; Franco, M.; Dimiccoli, V.; Tolomeo, A.; Scilimati, A.; Luisi, R.
Pharmaceutical development of novel lactate-based 6-fluoro-L-DOPA formulations
Eur. J. Pharm. Sci. 2017, 99, 361-368
2016
2015
Pati, M. L.; Abate, C.; Contino, M.; Ferorelli, S.; Luisi, R.; Carroccia, L.; Niso, M.; Berardi, F.
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate P-glycoprotein (P-gp) activity from 2 receptor affinity in mixed P-gp/σ2 receptor agents
Eur. J. Med. Chem. 2015, 89, 691-700
2014
Degennaro, L.; Zenzola, M.; Trinchera, P.; Carroccia, L.; Giovine, A.; Romanazzi, G.; Falcicchio, A.; Luisi, R.
Regioselective functionalization of 2-arylazetidines: Evaluating the ortho-directing ability of the azetidinyl ring and the α-directing ability of the N-substituent
Chem. Commun. 2014, 50, 1698-1700